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With the right treatment and care, many children with immunodeficiency can lead healthy, active lives. In this blog, the leading Dr. Gaurav Mandhan, pediatrician in Gurgaon provides insight into how immunodeficiency in kids is treated, from medications to advanced therapies, helping parents understand the best ways to manage immunodeficiency in pediatrics.
1. Antibiotic and Antiviral Therapy
Children with immunodeficiency may suffer from frequent bacterial or viral infections. To manage this:
● Antibiotics are given regularly to prevent infections.
● In cases of viral infections, antiviral drugs may be prescribed.
● Your doctor may advise long-term antibiotic prophylaxis to avoid repeat infections like pneumonia or ear infections.
Quick treatment of infections is important to avoid complications.
2. Immunoglobulin Replacement Therapy
This is one of the most effective treatments for primary immunodeficiency, especially when the child has low antibody levels.
● IVIG (Intravenous Immunoglobulin): Administered via a drip once every 3–4 weeks in a hospital.
● SCIG (Subcutaneous Immunoglobulin): Given under the skin weekly, and can sometimes be done at home.
These antibodies help your child’s body fight off infections more effectively. This is safe, effective, and improves long-term immunity.
3. Stem Cell or Bone Marrow Transplant
For severe types like Severe Combined Immunodeficiency (SCID) or Wiskott-Aldrich Syndrome, a stem cell transplant may be considered.
● Healthy donor stem cells are transplanted to build a new, functioning immune system.
● The best results occur when the transplant is done at an early stage.
● Though not needed for every child, this option can be curative in some severe cases.
4. Gene Therapy
This is a promising new treatment for certain types of inherited immunodeficiencies.
● It involves correcting the faulty gene that causes the disorder.
● Currently available only at advanced research centers.
● While still evolving, gene therapy offers hope for a permanent treatment in specific cases.
5. Nutritional Support and Immune Boosting Diet
A balanced and nutritious diet is crucial:
● Include protein-rich foods, fruits, vegetables, whole grains, and healthy fats.
● Nutrients like Zinc, Iron, Vitamin A, C, D, and Folic Acid support immune health.
● Children with secondary immunodeficiency due to malnutrition may show remarkable improvement with dietary changes alone.
● Avoid junk food and processed snacks that lower immunity.
6. Vaccination Precautions
Children with immunodeficiency should follow a customized vaccination schedule:
● Vaccines like MMR, Varicella may be unsafe for some children.
● However, inactivated vaccines are usually safe and necessary.
● Always follow your pediatric immunologist’s guidance on which vaccines are safe.
7. Regular Monitoring and Specialist Care
Treatment doesn’t end with medicines. Children with immunodeficiency require:
● Regular follow-ups with a pediatric immunologist
● Blood tests to monitor immune function
● Early treatment of infections
● Growth tracking and developmental assessment
With proper care, most kids can attend school, play, and live normal lives.
Where to Seek Treatment?
If you suspect your child may have an immune deficiency, seek help from a pediatrician near you for immunodeficiency disorders. Early diagnosis and the right treatment plan can make a significant difference in your child’s health and development.
Conclusion:
Treating immunodeficiency in children requires a multifaceted approach. From medications and antibody therapy to nutritional support and long-term care, every step plays a vital role in helping your child grow up healthy and strong. If your child has frequent infections or low immunity, don’t wait. Consult a pediatrician near you for expert care.

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